Are MUSE Cells Available in the United States?
BLUF: Yes — MUSE cells are available in the United States through physician-supervised programs at select regenerative medicine centers. Springs Rejuvenation holds one of the few authenticated sources of Dezawa-method MUSE cells in the country, available at locations in Miami, New York, Los Angeles, Austin, and Atlanta. Patients no longer need to travel overseas for access to a physician-supervised US MUSE cell program.
The Short Answer: Yes, With Important Caveats
MUSE cells (Multilineage-Differentiating Stress-Enduring cells) originated in Japan, where most foundational research and clinical trials have taken place. Dr. Mari Dezawa of Tohoku University discovered them in 2010, and Japan's Life Science Institute developed the most advanced MUSE cell product (CL2020). For years, patients who had read the research and wanted access faced a difficult reality: no credible US MUSE cell supply existed.
That has changed. Springs Rejuvenation has established access to authentic Dezawa-method MUSE cells — isolated using the validated SSEA-3 marker and sourced from an FDA approved lab — for physician-supervised, off-label clinical programs at our US centers.
Why Most US Clinics Don't Offer Authentic MUSE Cells
This is a critical distinction patients must understand. MUSE cells are a specific subpopulation of mesenchymal stem cells (MSCs), representing approximately 1–3% of the total MSC pool. They are identified and isolated by the SSEA-3 surface marker, typically using fluorescence-activated cell sorting (FACS) — a process that is not standard in most clinical stem cell labs.
Many US clinics that advertise "MUSE cells" are, in practice, offering standard MSC preparations that have not been specifically sorted for the SSEA-3 marker. While MSCs have their own evidence base, they are not the same as authenticated MUSE cells. As Dr. Charles Pereyra, MD, I make this point clearly in every initial consultation: patients asking specifically about MUSE cells deserve to know whether what they are being offered has been validated as such. At Springs Rejuvenation, we can confirm our cell preparations meet Dezawa-method standards.
The Regulatory Context in the US
MUSE cell programs in the United States are investigational and not FDA approved therapy. Springs Rejuvenation's cell preparations are produced in an FDA approved lab, and all programs are in the experimental stages. All patients receive comprehensive informed-consent discussion before any procedure, and MUSE cell programs at Springs are administered under physician supervision.
This is not an overseas operation. Springs Rejuvenation is a US-based medical practice. Patients do not need to travel to Mexico, Panama, the Cayman Islands, or Japan to access an authenticated MUSE cell program — the supply is here, the physician oversight is here, and the follow-up care is here.
What to Expect at Springs Rejuvenation
Every patient who inquires about MUSE cell programs at Springs Rejuvenation goes through a formal consultation process. This includes:
- A review of your health history and current medical situation
- A discussion of the current evidence base for MUSE cells and realistic expectations
- Full informed-consent documentation, including the investigational nature of the protocol
- A physician-supervised care plan developed by Dr. Pereyra or the supervising physician at your location
- Access to follow-up evaluation and ongoing care coordination
We do not promise specific outcomes. Individual results depend on many factors.
Springs Rejuvenation US Locations
MUSE cell consultations are available at all five Springs Rejuvenation centers:
- Miami / Aventura, FL: 2820 NE 214th St, Suite 801 — (786) 980-9543
- New York City, NY: 245 5th Ave, Suite 307 — (646) 859-0286
- Los Angeles, CA: 420 E 3rd St, Suite 705 — (213) 725-2361
- Austin, TX: 8700 Menchaca Rd, Suite 602 — (512) 866-1655
- Atlanta, GA: 1800 Peachtree St NW, Suite 660 — (470) 735-7447
For more background on what differentiates authentic MUSE cells from conventional stem cell preparations, see our article on why MUSE cell provenance matters. To understand the science, see our physician's guide to MUSE cells.
Frequently Asked Questions
Are MUSE cells FDA approved in the US?
MUSE cell programs are not an FDA approved therapy and are in the experimental stages in the United States. Springs Rejuvenation's cell preparations are produced in an FDA approved lab. All programs are conducted under physician supervision with full informed consent.
Do I need to go overseas to get MUSE cells?
No. Springs Rejuvenation offers physician-supervised MUSE cell programs at US locations in five major metro areas: Miami, New York, Los Angeles, Austin, and Atlanta. You do not need to travel to Japan, Mexico, or elsewhere to access our programs.
How do I know if a clinic truly offers authentic MUSE cells?
Ask about the isolation methodology (SSEA-3 marker, FACS-based sorting), the laboratory source (FDA approved lab?), and the specific batch documentation. Springs Rejuvenation can provide documentation of our cell preparation methodology. If a clinic cannot answer these questions specifically, the "MUSE cells" label may not be accurate.
Springs Rejuvenation is a physician-led regenerative medicine practice with locations in Miami, New York, Los Angeles, Austin, and Atlanta. Dr. Charles Pereyra, MD, serves as medical director. All regenerative programs are administered under physician supervision.
Disclaimer: Springs Rejuvenation's cell preparations are produced in an FDA approved lab, but are not an FDA approved therapy. This information is currently in the experimental stages — all information provided is based on our clinical experience and published research. These statements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Individual results depend on many factors. Always consult a qualified physician before beginning any regenerative protocol.