Facet Joint Pain: Regenerative Injections for Chronic Low Back Pain
Medically reviewed by Dr. Charles Pereyra, MD — Medical Director, Springs Rejuvenation. Last reviewed June 22, 2026.
Written by the Springs Rejuvenation regenerative medicine team from direct clinical experience administering stem cell and exosome protocols at our Aventura, Miami center.
The facet joints are small joints at the back of the spine that guide and limit movement, and they are a frequently overlooked source of chronic low back pain. When they become arthritic, the result is often a deep, aching pain that worsens with extension or twisting. Many patients want to know whether a regenerative injection can help, and for the right facet joint it is a reasonable option to discuss.
How facet joints cause pain
Like other joints, facet joints have cartilage surfaces that can wear over time. As they degenerate, the surrounding tissue becomes irritated and inflamed, producing the localized back pain characteristic of facet arthropathy. Because these joints are small and well-defined, they can be targeted with precise, image-guided injections.
What regenerative options aim to do
Cell-based and platelet-rich plasma approaches aim to support the joint environment and reduce symptoms rather than rebuild worn cartilage. At Springs Rejuvenation any facet-directed injection is delivered with image guidance and built into a broader plan that includes the core strengthening and movement work that protects the spine over time.
Reading the evidence honestly
Evidence for regenerative injections in facet joints is earlier than the larger body of knee research, so claims should stay measured. Some patients report meaningful relief lasting several months, which can be valuable for someone trying to stay active and reduce reliance on other measures. Advanced, multi-level degeneration may respond less, and we are honest about that.
How is the facet joint located accurately?
Image guidance helps confirm that the injection reaches the intended joint, which matters for both safety and results.
Who is usually a candidate?
Patients whose pain is confirmed to come from the facet joints, and who want to try a regenerative route, tend to be the best fit. Identifying the true pain source first is essential.
What else should I be doing?
Core strengthening, movement, and load management remain central. Regenerative support is added to those fundamentals, not a substitute for them.
The Springs approach
We confirm that the facet joints are the real source of your pain, then decide together whether a regenerative plan is reasonable. A free consultation is the simplest way to get a grounded assessment of your low back pain.
Medical Disclaimer: Stem cell and exosome therapy is not an FDA approved therapy and is considered to be in the experimental stages. These statements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Springs Rejuvenation processes exosomes in an FDA approved lab. Individual results may vary. This content is reviewed for medical accuracy by Dr. Charles Pereyra, MD, Medical Director of Springs Rejuvenation, and is provided for educational purposes only. Always consult a qualified physician.